About
Mauro Adamo is a Professor in the Department of Chemistry at the Royal College of Surgeons in Ireland (RCSI), with expertise in synthetic organic and medicinal chemistry. He has held progressive academic positions at RCSI since 2002, including Lecturer (2002–2007), Senior Lecturer (2007–2010), and Professor (2010–present). He obtained his PhD from the University of Sheffield (2001) and a Doctoral Degree from the University of Florence (1997).
His research focuses on developing synthetic methodologies for drug discovery and production, with emphasis on enantioselective fluorination (including 18F labeling), phase transfer catalysis, and hypervalent sulfur chemistry. He leads the MFAA research group, which has published over 60 papers and secured 5 patents. Key research areas include:
- Design of novel organocatalysts for asymmetric synthesis
- Continuous flow processes for pharmaceutical manufacturing
- Radiolabeled compounds for medical imaging
- Sustainable synthesis of HIV therapeutics
Adamo's recent publications show interdisciplinary collaboration, with chemical research (e.g., desulfurative reactions, nucleoside synthesis) complemented by clinical co-authored works in neurosurgery. Chemistry articles emphasize green synthesis and catalytic innovation, while neurosurgery contributions focus on pediatric conditions and trauma management.
He has led 51 funded projects, including major grants from Science Foundation Ireland, Enterprise Ireland, and Horizon 2020. Notable projects:
- Novel Therapeutics Targeting FcgRIIa receptor (2024–2026)
- Preparation of 18F-labeled RNAs (2022–2023)
- Enantioselective fluorination for agrochemical/drug labeling (2018–2021)
- Flow chemistry processes for Paricalcitol synthesis (2018–2021)
Professional memberships include the American Chemical Society and Royal Society of Chemistry. He has supervised multiple PhD/MSc students in organic synthesis and medicinal chemistry.
