Mary Ryan

Mary Ryan is an Assistant Professor at the University of Wisconsin–Madison. Her research focuses on clinical trial design and analysis, particularly in the context of Alzheimer’s disease and correlated data. Key areas include methodological advancements for stepped-wedge cluster randomized trials and improving trial protocols for cognitive impairment studies.

Her work emphasizes statistical rigor in evaluating treatment efficacy and addressing challenges in participant dynamics, such as study partner roles and endpoint stability. Ryan’s contributions span biostatistical methodology, software development (e.g., the ORTH. Ord R package), and interdisciplinary applications in neurology and public health.

Publications highlight trends in adaptive trial designs, covariate handling, and sequential sampling techniques. Notable topics include the impact of study partner replacement, biomarker disclosure barriers in preclinical trials, and statistical methods for clustered data.

No scientific awards are explicitly listed in the provided materials. Her research has implications for improving clinical trial efficiency and patient-centered outcomes in neurodegenerative diseases.