Marutpong Detarya

Marutpong Detarya, PhD, is a Postdoctoral Associate in the Department of Therapeutic Radiology at Yale School of Medicine, Yale University. He holds a PhD in Medical Biochemistry and Molecular Biology from Khon Kaen University (2021) and a BSc (Honors) in Medical Technology from the same institution (2012). His research focuses on glycobiology, particularly the role of protein glycosylation in cancer progression, with a focus on cholangiocarcinoma (CCA). He has conducted research at Kumamoto University in Japan, studying O-GalNAcylation’s impact on CCA and EGFR signaling. His current work involves CRISPR-based genome editing to model PIK3CA mutations in head and neck squamous cell carcinoma (HNSCC).

Education:

• PhD in Medical Biochemistry and Molecular Biology, Khon Kaen University, 2021
• BSc (Honors) in Medical Technology, Khon Kaen University, 2012

Research Interests: His research integrates glycobiology, cancer biology, and molecular biology to explore how glycosylation pathways influence tumor progression. Key areas include O-GalNAc glycosylation, cancer stem cells, and CRISPR-based mutagenesis in therapeutic modeling. He investigates the interplay between metabolic stress (e.g., lactic acidosis) and signaling pathways like EGFR/STAT3 and AKT/ERK in CCA aggressiveness.

Articles Trends: His publications highlight cholangiocarcinoma as a central focus, with studies on glycan binding, EGFR modulation, and metabolic drivers of malignancy. Recent work explores CRISPR-generated mutation models to uncover therapeutic strategies for HNSCC. The majority of his research combines proteomics, molecular biology, and drug screening to address unmet clinical needs in cancer treatment.

Awards:

• Outstanding Thesis Award (Doctoral Level, Health Sciences), 2022
• Outstanding Oral Presentation (7th International Biochemistry Conference), 2021
• Excellent Poster Presentation (11th Asian Glycoscience Conference), 2019

Advising/Grants: While currently a postdoctoral researcher, his training includes roles as a research assistant and collaborations with Prof. Sopit Wongkham and Prof. Joseph N. Contessa. His work aligns with Yale’s Therapeutic Radiology initiatives in precision oncology and genomic editing.

Labs/Teams: He is affiliated with Prof. Joseph N. Contessa’s lab at Yale, focusing on CRISPR-based cancer models. Previous affiliations include Prof. Wongkham’s lab at Khon Kaen University and the Department of Tumor Genetics and Biology at Kumamoto University.