Martin Rennie

Dr. Martin Rennie is a Researcher at the University of Glasgow, affiliated with the School of Molecular Biosciences. He utilizes cryo-electron microscopy, biophysics, and biochemistry to study protein molecular functions, particularly in DNA repair and ubiquitination pathways.

• PhD: University of Auckland, New Zealand (Lab of Dr. Richard Kingston)
• Postdoc: University of Galway, Ireland (Lab of Prof. Peter Crowley)
• Current Postdoc: University of Glasgow (Lab of Prof. Helen Walden)

His research explores structural biology and the biochemical mechanisms of protein-protein interactions, focusing on FANCI-FANCD2 complexes and USP1 inhibition. Publications highlight advancements in understanding ubiquitination machinery regulation and the application of AlphaFold in protein structure prediction.

Key publications include structural analyses of the USP1-UAF1 complex, mechanistic insights into FANCD2 ubiquitination, and studies on allosteric regulation in DNA repair pathways. His work intersects with clinical biochemistry and molecular biology research.

• Scientific Awards: Wellcome Trust Grant (2021-2022) for "Structural basis of Hsp90-CHIP association"

Dr. Rennie collaborates with researchers like Prof. Helen Walden, Connor Arkinson, and Viduth K. Chaugule. His recent studies emphasize the application of structural biology in elucidating protein function in DNA repair pathways.