Martin Fascione

Dr. Martin Fascione is a Reader in Chemistry at the University of York. He leads research at the interface of chemistry and biology, focusing on chemical glycobiology and glycomedicine. His work employs synthetic chemistry, enzymology, and bioconjugation to study carbohydrate roles in disease and develop therapeutic tools.

Research interests include the chemical glycobiology of nonulosonic/sialic acids, synthetic and enzymatic carbohydrate chemistry, and protein bioconjugation. His group investigates bacterial pathogen recognition, tumor metastasis, and immunological responses mediated by glycans.

Recent publications demonstrate a focus on bacterial glycans, enzyme mechanisms, glycoconjugate therapeutics, and diagnostic tools. Trends include structural enzymology, chemoenzymatic synthesis, glycan-based sensors, and bioorthogonal chemistry applications.

Awards:

• ERC Consolidator Grant (2022)
• Marie Curie International Outgoing Fellowship (2012-2014)

Dr. Fascione directs an interdisciplinary lab collaborating with structural biologists and clinicians. His ERC grant supports research on pseudaminic acid sugars in infectious diseases.