Marta M. Lipinski

Marta M. Lipinski, PhD, is an Associate Professor in the Department of Anesthesiology at the University of Maryland School of Medicine, with secondary appointments in Neurobiology. She holds affiliations with the Shock, Trauma and Anesthesiology Research (STAR) Center, Center for Stem Cell Biology and Regenerative Medicine, and Center for Biomolecular Therapeutics. Her laboratory focuses on autophagy mechanisms in neurotrauma, neurodegeneration, and brain aging.

Education includes:

• BA in Biology from Indiana University, Bloomington
• PhD in Cancer Biology from Massachusetts Institute of Technology
• Postdoctoral training at Harvard Medical School

Research interests center on:

• Autophagy dysregulation in traumatic brain/spinal cord injury
• Lysosomal membrane damage mechanisms
• Neuroinflammation-microglia interactions
• Lipid metabolism in neurodegeneration
• Connections between TBI and age-related disorders

Her work utilizes transgenic mouse models, high-throughput screening, and multi-omics approaches.

Publication trends show consistent focus on:

• Autophagy-lysosomal dysfunction in acute CNS injuries
• Molecular crosstalk between neurotrauma and neurodegeneration
• Microglial activation patterns in aging brains
• Therapeutic targeting of lipid metabolism pathways

Active NIH grants support:

• Cell-type specific multi-omics of brain aging (R33 AG076858)
• Autophagy mechanisms in spinal cord injury (2R01 NS094527)
• TBI-neurodegeneration linkage (R01 NS091218)
• Biomarker development for TBI diagnosis (FDA U01FD005946)

Lab leadership includes:

• Current members: 2 PhD students, 1 assistant professor, 1 lab assistant
• Collaborations across 10+ UMB departments and external institutions
• Undergraduate/medical student training initiatives