Mark E.S. Bailey

Dr. Mark E.S. Bailey is a Senior Lecturer at the School of Molecular Biosciences, University of Glasgow, with a focus on human genetics and molecular genetics. His work spans Mendelian and complex disorders, including psychiatric conditions, metabolic diseases, and neurogenetic syndromes like Rett syndrome. He actively collaborates in biobank-scale studies and gene therapy research.

His research interests include mapping disease genes, molecular pathology, gene therapy, and the interplay between genetic variation and traits such as mood instability, obesity, and circadian rhythms. He investigates gene-environment interactions in metabolic disorders and has contributed to understanding the genetic basis of Rett syndrome, Ménière disease, and psychiatric comorbidities.

Recent publications highlight his work on

• circadian gene variation
• polygenic risk for Alzheimer’s and schizophrenia
• gene therapy in Rett models
• genetic links between mood and metabolism

His studies often integrate large datasets like UK Biobank, emphasizing trans-ancestry analysis and cross-disorder correlations.

Grants from organizations like the Rett Syndrome Association Scotland and Chief Scientist Office support his work on gene therapy and molecular mechanisms of neurogenetic disorders. He teaches genetics and bioinformatics at both undergraduate and postgraduate levels.