Mark D. Krieger

Mark D. Krieger, MD is Professor of Clinical Neurological Surgery at the Keck School of Medicine of the University of Southern California, where he also serves as Senior Vice President and Surgeon-in-Chief, and Medical Director of the Neurological Institute at Children's Hospital Los Angeles (CHLA). With over 30 years of academic and clinical experience, Dr. Krieger specializes in pediatric neurosurgery with a focus on complex conditions including hydrocephalus, Chiari malformation, and pediatric brain tumors.

Dr. Krieger's research spans multiple domains within pediatric neurosurgery. His primary interests include hydrocephalus management and shunt-related complications, Chiari malformation and syringomyelia, pediatric brain tumors and their molecular characteristics, and surgical outcomes research. As a principal investigator in the Hydrocephalus Clinical Research Network and the Park-Reeves Syringomyelia Research Consortium, he has led numerous multi-institutional studies examining best practices and outcomes in pediatric neurosurgical conditions.

Analyzing his recent publication trends reveals a strong emphasis on evidence-based approaches to pediatric neurosurgical conditions. His work frequently addresses health disparities in neurosurgical outcomes, particularly racial disparities in hydrocephalus management. Dr. Krieger has made significant contributions to understanding shunt complications, optimizing timing of interventions in hydrocephalus, and advancing the molecular characterization of pediatric brain tumors. His research consistently bridges clinical practice with scientific investigation to improve outcomes for children with neurological conditions.

Dr. Krieger maintains active involvement in surgical education and training, having contributed to studies on pediatric neurosurgery residency training in the United States. His leadership extends to national organizations, including the American Society of Pediatric Neurosurgeons, where he has provided guidance during critical periods such as the COVID-19 pandemic. His work with the Hydrocephalus Clinical Research Network has established important quality improvement initiatives, including the role of antibiotic-impregnated catheters in reducing shunt infections.