Mark Abe

Mark Abe is a Professor at the University of Chicago, specializing in mitogen-activated protein kinases (MAPKs) and their roles in lung biology and cell signaling. His research focuses on ERK8 and ERK7, novel MAPKs involved in oxidative stress responses, apoptosis, and airway disease mechanisms.

• NIH Funding: R01HL073132 (2003-2008), K08HL003867 (1998-2003), F32HL009074 (1994)
• Key Collaborators: Marsha Rosner, Julian Solway, Michael Hershenson

Research Themes:
Dr. Abe’s work explores MAPK signaling pathways in lung epithelial cells and airway smooth muscle, particularly how oxygen intermediates and mitogen-activated kinases contribute to respiratory diseases. His publications highlight apoptosis regulation, cytokine production, and calcium signaling in airway injury models.

Publication Trends:
His 15 most recent articles (1996-2009) span Biochemistry, Cell Biology, and Pulmonary Medicine, with subfields including MAP Kinase Pathways, Lung Development, Ion Channel Regulation, Angiogenesis, Signal Transduction, and Reactive Oxygen Species.

Department Affiliation:
Dr. Abe collaborates with colleagues in the Department of Medicine (e.g., Fatima Ajmal, Romeen Lavani) and interacts with researchers in Pulmonary and Critical Care domains.