Mark A. Lovell

Mark A. Lovell, PhD, is a Professor & Chair in the Department of Chemistry at the University of Kentucky, affiliated with the Sanders-Brown Center on Aging. His work focuses on biomarker development for cognitive impairment and dementia, integrating neuroimaging and fluid-based diagnostics to advance precision medicine approaches.

• Current research aligns with Alzheimer's Disease Research Center (ADRC) initiatives, emphasizing blood and imaging biomarkers to discriminate dementia pathologies.
• His lab contributes to national consortia like MarkVCID and ADRC networks, aiming to replace invasive diagnostics with non-invasive tests.

The core he co-leads has pioneered discoveries linking cerebrospinal fluid/plasma biomarkers to brain imaging patterns and identified inflammatory markers tied to cerebrovascular disease.

Collaborations span multidisciplinary teams (e.g., with Brian T. Gold, Peter Nelson, and Gregory Jicha) to develop state-of-the-art tools for measuring protein changes and metabolic reprogramming in dementia pathologies.