Margreet Wolfert

Margreet Wolfert is a Researcher at the Chemical Biology and Drug Discovery group within the Department of Pharmaceutical Sciences, Faculty of Sciences, Utrecht University (Netherlands). Her career spans multiple prestigious institutions including the University of Georgia (USA) and University of Birmingham (UK).

Education

• Ph.D. in Biochemistry/Cancer Studies, University of Birmingham, UK (1998)
• M.Sc. in Biochemistry/Toxicology, University of Birmingham, UK (1995)
• H.B.O.-B in Medical-Chemical Direction, Van 't Hoff Instituut, Netherlands (1983)

Research Interests focus on chemical biology of glycans, including

• Chemoenzymatic synthesis of complex carbohydrates
• Structure-function analysis of glycan-protein interactions
• Design of synthetic vaccines targeting MUC1 and TLRs
• Role of glycosylation in adaptive/innate immune activation
• Development of bioorthogonal labeling techniques
• Modulation of heparan sulfate and lipid A derivatives

Scientific Trends from her publications reveal expertise in

• Glycan-based diagnostics for autoimmune diseases
• Influenza A virus receptor binding specificity
• Engineering nanoparticles for targeted cancer delivery
• Multi-component vaccine design with Toll-like receptor agonists
• Chemical reporter strategies for glycoprotein visualization
• Cu-free click chemistry for living cell labeling