
About
Marco Foiani is a Full Professor in Molecular Biology at the University of Milan and Scientific Director of IFOM (FIRC Institute of Molecular Oncology Foundation). He leads the 'Genome Integrity Laboratory' at IFOM since 2002 and holds positions at the European School of Molecular Medicine (SEMM) and the European Center for Nanomedicine (CEN). His research focuses on eukaryotic chromosome dynamics, DNA replication mechanisms, and genome integrity regulation. Key contributions include elucidating checkpoint-mediated control of stalled replication forks, CDK1's role in DNA damage response, and SUMOylation's function in replication fork protection.
Education:
- PhD in Molecular Biology, University of Milan (1988)
- NIH Postdoctoral Fellowship under Dr. Alan Hinnebush, Washington DC (1989-1991)
Research Interests: His work bridges molecular biology and oncology, addressing how DNA replication forks handle damage, transcription-replication conflicts, and telomere integrity. Recent studies highlight topoisomerase roles in replication topology and ATM-dependent regulation of terminal forks.
Awards:
- EMBO Membership (2010)
- Italian Society of Biophysics & Molecular Biology Award
- Chiara D’Onofrio Prize
- Biotec Award (Amgen & Dompé)
Professional Activities: Editor for Cell; organizer of international conferences on DNA replication and chromosome dynamics. No grants explicitly listed in texts, though his lab's activities imply extensive funding support.
Labs/Teams: Directs the Genome Integrity Laboratory at IFOM, collaborating with groups like the Branzei and Bermejo research teams on replication stress and repair mechanisms.
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