Marco Centanni

Marco Centanni is a Full Professor at the Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome. His research focuses on thyroid autoimmunity, endocrine-metabolic interactions, and the impact of gastrointestinal factors on thyroid hormone homeostasis.

Research interests include:

• Thyroid-microbiota axis
• Gastric pH effects on levothyroxine absorption
• Autoimmune polyendocrine syndromes
• Thyroid cancer outcomes

His recent publications analyze trends in thyroid autoimmunity, microbiota interactions, and gastric factors affecting thyroxine therapy. Key projects include in vivo studies on gastric acidity and pharmacological homeostasis in hypothyroid patients.

Scientific contributions involve:

• Elucidating T3's role in skeletal muscle atrophy
• Novel thyroxine formulations for malabsorption
• Thyroid-entero-gastric autoimmunity

He investigates intestinal barrier permeability in Hashimoto's progression and leads multicenter studies on thyroid cancer staging systems (AJCC/TNM 8th edition). His work bridges clinical endocrinology with molecular pathophysiology and pharmacological optimization.