Marc Schmidt-Supprian

Prof. Marc Schmidt-Supprian is a tenure-track Professor of Immunopathology and Signal Transduction at the Technical University of Munich (TUM), affiliated with the TUM School of Medicine and Health. His research focuses on autoimmune diseases and immune system cancers using genetically modified mice models. He holds a PhD from the University of Cologne and Harvard Medical School (2003), and conducted postdoctoral work at Harvard Medical School (2004–2007). He leads the DFG Emmy Noether Research Group established in 2007 at the Max Planck Institute of Biochemistry. His work bridges molecular immunology with clinical insights into immune dysregulation.

Research Interests:

• Autoimmune disease mechanisms
• Cancer immunology
• T cell receptor signaling
• Regulatory T cell biology
• Mast cell inflammation pathways
• Genetic models of immune system disorders

Publications Trends: His work emphasizes T cell regulation, inflammatory signaling, and genetic knockout models. Key contributions include defining TCR signaling in regulatory T cells and uncovering A20's role in mast cell-mediated inflammation.

Awards:

• DFG Emmy Noether Research Group (2007)

Advising & Grants: As a DFG Emmy Noether awardee, he has built a research group focused on immune system pathologies. While student names are not listed here, his lab investigates translational immunology with potential clinical applications.

Labs/Teams: Leads the Immunopathology and Signal Transduction group at TUM, integrating molecular, cellular, and systems-level approaches to study immune dysregulation.