
Marc Diamond
Professor · Neurodegenerative Diseases
University of Texas Southwestern Medical CenterAbout
Marc Diamond, M.D., is a Professor of Neurology and Neuroscience at UT Southwestern Medical Center. He previously served as the David Clayson Professor of Neurology at Washington University in St. Louis (2009-2014) and held faculty positions at UCSF (2002-2009). As founding director of the Center for Alzheimer's and Neurodegenerative Diseases (CAND), he leads a multidisciplinary team investigating protein aggregation mechanisms in neurodegenerative diseases.
- Education: M.D. from UCSF (1993), history degree from Princeton
- Key Contributions: Discovered cell-to-cell propagation of tau protein aggregates, linking Alzheimer's to prion biology
His research focuses on tauopathies, prion-like protein propagation, and translational therapeutics. He has developed methods for detecting proteopathic seeding activity now used globally, holds multiple patents, and invented a monoclonal antibody in clinical trials for Alzheimer's therapy. His work has profoundly impacted understanding of neurodegenerative disease progression and therapeutic strategies.
Laboratory: The Diamond Lab trains postdocs, graduate students, and staff in multidisciplinary approaches to neurodegeneration, emphasizing cellular models and molecular mechanisms of protein aggregation.
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