Manuel Rosa-Garrido

Dr. Manuel Rosa-Garrido is an Assistant Professor in Biomedical Engineering at UAB, with joint affiliation in the Heersink School of Medicine. He holds BS degrees in Biology and Biochemistry from Spanish universities and a PhD in Biomedicine from University of Cantabria, followed by postdoctoral training at UCLA. His lab studies chromatin reorganization in heart failure using epigenomic approaches.

Research focuses on epigenetic mechanisms in cardiovascular disease, employing chromosome conformation capture (Hi-C), chromatin accessibility (ATAC-seq), and gene expression profiling. His work bridges cancer epigenetics with cardiac pathology to identify structural biomarkers.

Key publications examine chromatin remodeling in cardiac myocytes, pathological hypertrophy, and nuclear architecture. His team compares chromatin dynamics in human heart tissue across disease stages to develop epigenetic therapies.