Malte Gersch

Dr. Malte Gersch is a researcher in Chemical Biology at TU Dortmund University's BioMedizin-Zentrum, where he leads an active research group investigating proteolytic enzymes within the ubiquitin system and developing novel therapeutic approaches through enzyme manipulation.

His laboratory employs a multidisciplinary methodology spanning:

• Proteolytic enzyme mechanisms
• Ubiquitin system biochemistry
• Organic synthesis of enzyme modulators
• Structural biology approaches
• Cellular assay development
• Therapeutic opportunity exploration

Dr. Gersch's work bridges chemical biology and drug discovery, focusing on hijacking natural proteolytic processes for medical applications, with potential relevance to cancer and neurodegenerative disease research.

His research group consists of multiple team members working collaboratively on various aspects of enzyme-targeted therapeutics.