López-Otín Carlos

Professor · Analysis of tumour progression susceptibility in the models generated

Austria

About

Carlos López-Otín is a Professor of Biochemistry and Molecular Biology at Oviedo University since 1987. His research focuses on proteases in tumour processes and their role in cancer progression.

Fields: Tumour progression, proteolytic activity inhibition, animal models of proteolytic function, protease characterization, and structural analysis.

Scientific Awards:

Member of the Royal Academy of Sciences-Spain
Member of the Academia Europaea
"Santiago Ramon y Cajal" National Award for Research
'Carmen and Severo Ochoa' Award for Molecular Biology
'King Jaime I' Basic Research Award
European Biochemistry FEBS Prize '25th Silver Jubilee'

Research fields

Analysis of tumour progression susceptibility in the models generated Development/Study of strategies which inhibit proteolytic activity of tumour proteases Generation of animal models of gain and loss of proteolytic function Identification of and enzymatic and functional characterization of proteases associated with tumour processes Determination of three dimensional structures of human proteases associated with tumours

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