Lydia Scarfò

Lydia Scarfò is an Associate Professor at Vita-Salute San Raffaele University, affiliated with the Department of Internal Medicine under the School of Medicine. Her research focuses on prognostic factors in chronic lymphocytic leukemia (CLL), preneoplastic conditions like monoclonal B lymphocytosis (MBL), targeted therapies, and clinical trial design.

• Education: MD in Medicine and Surgery (University of Ferrara, 2006), specialization in Hematology (2012), specialization in Internal Medicine (2017).

Research Highlights: Active in preclinical and clinical studies for CLL and related disorders, leading a Phase 3 trial for follicular lymphoma therapy while co-investigating over 20 clinical trials. Her work explores molecular biomarkers like ATM aberrations, TP53 mutations, and U1 spliceosomal RNA mutations to improve CLL diagnostics and treatment.

Publications: Recent works include studies on the lymph node microenvironment in CLL, SARS-CoV-2 immune responses in treated patients, and novel combination therapies for Richter transformation. Her research has been published in journals like Leukemia, Blood Advances, and The Lancet Oncology.

Labs & Collaborations: Works at the San Raffaele Scientific Institute in Milan, contributing to the European Research Initiative on CLL (ERIC) and advancing clinical research methodologies.