Lucy G. Sinclair
Research Fellow · Antimicrobial Photodynamic Therapy
University of StrathclydeAbout
Lucy G. Sinclair serves as a Research Fellow in the Department of Biomedical Engineering at the University of Strathclyde, actively contributing to antimicrobial photodynamic therapy research with focus on violet-blue light applications. Her institutional affiliation spans multiple collaborative projects including the John Gaylor Fund and EPSRC-funded sepsis technology development.
Her educational background culminates in a 2024 doctoral thesis titled Performance and energy efficiency of low irradiance antimicrobial violet-blue light for environmental decontamination applications, supervised by Professors Maclean and MacGregor at Strathclyde.
Dr. Sinclair's research centers on light-based pathogen inactivation with specialization in 405-nm wavelength systems for bacterial/viral decontamination. Key methodologies include
- Energy-efficient antimicrobial protocols
- Biofilm engineering for infection modeling
- Extracorporeal sepsis treatment technology
- Viral surrogate validation (Phi6/SARS-CoV-2)
Recent publication trends demonstrate consistent advancement in low-irradiance photodynamic systems, showing improved energy efficiency while maintaining antimicrobial efficacy across bacterial (Staphylococcus aureus) and viral targets. Her dual focus on fundamental light-matter interactions and clinical translation defines her research trajectory.
Scientific recognition includes:
- Engineering and Physical Sciences Research Council (EPSRC) Doctoral Prize 2024
Grant leadership features:
- Principal Investigator
- Development of Novel Dual-targeted Extracorporeal Technology for Sepsis (2024-2025) Co-investigator
- John Gaylor Collaborative Fund: 3D-bioprinted biofilms project (2025-2026)
Active participation in the Strategic Themes Bioimaging Workshop (2024) demonstrates integration within Strathclyde's interdisciplinary research ecosystem, particularly in photobiology applications for healthcare.
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