Lucy Crooks

Dr. Lucy Crooks is a Senior Lecturer in Genomics and Bioinformatics at Sheffield Hallam University, with an honorary lecturing role at the University of Sheffield. Her academic journey includes a Natural Sciences BA from the University of Cambridge, a PhD in malaria infection modeling from Edinburgh, and postdoctoral research at ETH Zurich (HIV fitness mutations), Swedish University of Agricultural Sciences (QTL analysis in pigs), and the Wellcome Trust Sanger Institute (UK10K sequencing project). She previously led bioinformatics at Sheffield Diagnostic Genetics Service (NHS), focusing on NGS data pipelines for clinical diagnostics.

Her research interests center on next-generation sequencing (NGS) applications for disease genetics, including epistasis analysis and clinical variant prioritization. She teaches bioinformatics modules for biomedical science programs, emphasizing hands-on computational training. She is a founding member of the Sheffield Bioinformatics Hub and collaborates across institutions to advance genomic medicine.

Teaching responsibilities include courses on Human Genomics, Proteomics, and Biomedical Laboratory Techniques. Current research focuses on leveraging NGS to uncover genetic causes of disease, with emerging projects in statistical modeling of genetic interactions.