Lucas Paoli

Lucas Paoli is a Researcher and Course Instructor at École Polytechnique Fédérale de Lausanne (EPFL), Switzerland. He leads the Paoli Lab (Microbiome Immunity and Ecology) within the Global Health Institute (GHI) under the School of Life Sciences (SV). His roles include scientific collaboration and teaching responsibilities in life sciences engineering. Paoli holds a PhD in Microbiome Research from ETH Zürich (2018-2023), an M.Phil. in Environmental Policy from the University of Cambridge (2017-2018), and an M.Sc. in Ecology and Evolution from École normale supérieure (2015-2017).

Research Focus: His work bridges microbial immunity and ecology, investigating how microbes defend against viral infections across ecosystems like oceans and human microbiomes. Techniques include global-scale metagenomics and functional genomics to study immune strategies and ecological interactions. Key themes involve microbial community dynamics, viral defense mechanisms, and the impact of environmental factors on microbial immunity.

Lab & Education: The Paoli Lab explores microbiome-immunity interactions with a focus on ecological contexts. Paoli supervises PhD students in Life Sciences Engineering. His research outputs span microbial ecology, metagenomic tool development, and marine microbiome studies. Contact: lucas.paoli@epfl.ch, AAB 1 39, +41 21 693 16 99.