Lucas Hoffman

Lucas Hoffman is an Adjunct Professor in the Department of Microbiology and the School of Medicine at the University of Washington. Clinically, he specializes as a pediatric pulmonologist, focusing on chronic lung infections in children with cystic fibrosis (CF) and non-CF bronchiectasis.

• Research emphasizes novel approaches to studying and treating CF-related infections
• Key areas: microbiome dynamics, antibiotic resistance, and CFTR modulator therapies

Recent publications (2022-2025) analyze CF microbiota changes, Staphylococcus aureus pathogenesis, and impacts of elexacaftor/tezacaftor/ivacaftor. His work spans clinical trials, bacterial physiology, and diagnostic innovations, with collaborations across pediatrics, microbiology, and global CF research networks.