
About
Prof. Lothar R. Schad is a Professor at the Medical Faculty Mannheim, Heidelberg University, leading the Computer Assisted Clinical Medicine department. His research focuses on advancing magnetic resonance imaging (MRI) techniques for oncological radiotherapy planning and monitoring, including sodium imaging, diffusion tensor imaging, and lung/perfusion imaging. The group operates 3×1.5T and 2×3T MRI systems, with access to a 9.4T animal MRI system.
Key research areas include:
- Quantitative biomarker development for diagnosis and therapy monitoring
- Integration of multi-modal imaging (CT/MRI/PET)
- Development of high-resolution protocols for clinical applications
Current projects involve translational studies using animal models (rat/mouse) and bioreactor systems. Collaborations exist with radiology, neurology, and cardiology departments. Recent work emphasizes physiological MRI (perfusion, diffusion, oxygenation) in abdominal organs and sodium imaging for tissue viability assessment.
Notable contributions include ultra-high-resolution glomeruli imaging in rat kidneys (9.4T), clinical diffusion kurtosis applications, and lung perfusion/ventilation mapping at 1.5T. The team also develops image-guided interventions using robotic systems like ZEEGO.
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