Lisa Prendergast

Dr. Lisa Prendergast is a researcher at Newcastle University, specializing in molecular biology and cancer research. Her work focuses on DNA repair mechanisms, cell cycle regulation, and the development of targeted therapies. She has contributed to studies on synthetic lethality involving PARP and CHK1 inhibitors, mitotic chromatin dynamics, and DNA replication processes.

Her research interests span molecular oncology, epigenetics, and chemical biology innovations, such as DNA-encoded libraries. Notable collaborations include studies on R-loop resolution via the INO80 complex and the role of HP1 in mitotic chromatin regulation.

Dr. Prendergast's publications reflect a strong emphasis on translational research, bridging basic biology with clinical applications in radiotherapy and chemotherapy. She has explored centromeric protein complexes and their roles in chromatin assembly, demonstrating interdisciplinary expertise in genetics and cell biology.