Line Jacques

Line Jacques, MD, MS, is a Professor in the Department of Neurological Surgery at the University of California, San Francisco (UCSF) School of Medicine. With clinical expertise in pediatric and adult neurosurgery, she specializes in neurofibromatosis (NF1, Schwannomatosis), peripheral nerve surgery, and spinal cord electrophysiology.

• Education: MD from Universite de Montreal (1990), General Surgery Internship (Cliniques Universitaires Saint-Luc, 1991), Neurosurgery Residency (University of Montreal Hospital Saint-Luc, 1996), and Neurosurgery Fellowship (LSU Health Shreveport, 1997).
• Certifications: Board-certified in Neurological Surgery by the American Board of Neurological Surgery (2003).

Research Focus: Her work bridges clinical neurosurgery with translational research, emphasizing neurofibromatosis tumor biology, spinal cord stimulation for pain management, and peripheral nerve injury mechanisms. Key contributions include studies on epidural spinal electrograms for movement mapping, Schwann cell tumor dedifferentiation, and diagnostic accuracy of MRI for nerve sheath tumors.

Scientific Trends: Recent articles highlight advancements in spinal cord herniation pathophysiology, neuralgic amyotrophy diagnostics, and neurogenomic approaches to schwannomatosis. Earlier publications established foundational work in failed back surgery syndrome management via spinal cord stimulation.

Clinical Impact: Jacques co-authored high-impact trials like the PROCESS Study (2008) evaluating spinal cord stimulation versus conventional pain management, with over 250 citations. Her work informs surgical protocols for brachial plexus trauma and cervical nerve tumors.