Lin Han

Professor Lin Han is affiliated with the School of Biomedical Engineering, Science and Health Systems at Drexel University. His research focuses on nanoscale structure-property relationships of biomaterials, with applications in disease diagnostics, tissue regeneration, and bio-inspired material design. He leads the Nanobiomechanics Laboratory, integrating nanotechnology, biomechanics, and gene therapy.

• Education:
  • PhD in Bio- and Polymeric Materials, Massachusetts Institute of Technology (2007)
  • BE in Materials Engineering, Tsinghua University (2002)

His research interests include:

• Nanoscale biomechanics of extracellular matrix (ECM) biomolecules like aggrecan, decorin, and type V collagen.
• Understanding genetic origins of joint tissue diseases and mechanotransduction in cartilage.
• Developing stimulus-responsive biomaterials and ECM-inspired tissue engineering strategies.

The scientific awards he has received include:

• 2024 AIMBE College of Fellows
• 2024 NIH Grant for cartilage PCM mechanotransduction
• 2022 Drexel Faculty Award
• 2021 Kappa Delta Young Investigator Award
• 2016 Commonwealth CURE Program Grant

His research on articles demonstrates trends in ECM nanomechanics, collagen structure-function analysis, and osteoarthritis intervention using advanced imaging and molecular engineering. His work bridges biomaterial design and clinical applications for cartilage repair.

He has secured significant grants and collaborates on interdisciplinary projects involving MIT, Drexel, and industry partners. His lab develops novel hydrogels and nanoscale testing methods to study tissue degeneration and regeneration.