Lian Feenstra

Dr. Lian Feenstra is a researcher at the University of Groningen, focusing on vascular biology and chronic kidney disease. Her work investigates how calciprotein particles trigger endothelial cell dysfunction and vascular calcification.

• Active in UN Sustainable Development Goals (SDGs) related to health and well-being
• Key collaborations include TransplantLines Investigators and international researchers

Research Interests

Feenstra's research explores the interplay between calciprotein particles and vascular pathology in chronic kidney disease. She examines mechanisms like:

• Paracrine signaling between endothelial and smooth muscle cells
• Calcium overload and mitochondrial dysfunction in endothelial cells
• Nitric oxide metabolism impairment leading to endothelial dysfunction
• Vascular remodeling in uremic conditions
• Gene expression profiling in calcification processes

Publication Trends

Her recent articles (2023–2025) emphasize calciprotein particle dynamics, endothelial cell stress, and their role in cardiovascular complications of chronic kidney disease, with significant cross-disciplinary focus on cell biology and nephrology.