Li Li

Li Li serves as Assistant Professor in the Departments of Pharmacy Practice and Pharmaceutical Sciences at Texas Tech University Health Sciences Center's School of Pharmacy since 2023. Her interdisciplinary research bridges analytical chemistry, structural biology, and translational medicine to advance drug metabolism studies and biomarker discovery.

Her academic background includes:

• PhD, University of Texas at Arlington, 2014
• MS, Shenyang Pharmaceutical University, 2009

Dr. Li's research program focuses on elucidating molecular mechanisms in neurodegenerative diseases and cancer through advanced analytical methodologies. She employs mass spectrometry and cryo-electron microscopy to characterize disease biomarkers and protein modifications, with particular emphasis on tau protein pathology in Alzheimer's disease and oncological applications. Her work integrates structural biology with cell-based disease models to identify novel drug targets and diagnostic tools.

Her 2023 publication in Structure demonstrates her expertise in molecular neurodegeneration research, revealing how acetylation patterns stabilize tau fibril formation. This work exemplifies her broader research trajectory connecting structural insights with pathological mechanisms to develop therapeutic interventions.

No scientific awards are documented in her current profile.

Dr. Li mentors students through Directed Individual/Independent Study projects since 2024 and collaborates extensively with the North Texas cancer research community via the Clinical Pharmacology Cancer core. Her grant activities support analytical infrastructure for regional translational research initiatives.

She contributes to the North Texas Clinical Pharmacology Cancer core, providing mass spectrometry expertise and analytical support for biomarker validation and drug metabolism studies across multiple disease domains.