Lei Song

Lei Song is a researcher at the Yale School of Medicine, Department of Otolaryngology. With a PhD from Creighton University (2002) and MD from Shanghai Medical University (1991), their work focuses on auditory neuroscience and molecular mechanisms of hearing loss.

• Research Themes: Investigating cochlear frequency coding, synaptic vesicle trafficking, and transcriptional regulation of hair cell development
• Key Collaborations: Working with Joseph Santos-Sacchi, Jun-Ping Bai, and interdisciplinary teams in auditory genetics
• Publications: 8 peer-reviewed articles (2021-2025) on mechanisms underlying age-related and genetic hearing impairments
• Methodology: Combining molecular genetics, animal models, and advanced imaging techniques to study auditory system pathophysiology

Current Work examines how metabolic factors like high-fat diets affect cochlear aging, and explores therapeutic strategies for hair cell regeneration through gene expression modulation.