About
Lars Norlen is a Senior Lecturer affiliated with the Department of Medicine, Solna at Karolinska Institutet. His research focuses on the biophysical and structural analysis of the human skin barrier, utilizing advanced techniques such as cryo-electron microscopy (cryo-EM) and molecular dynamics (MD) simulations to investigate lipid organization, drug permeation mechanisms, and skin barrier formation.
Key research areas include:
- Biophysics of lipid membranes
- Structural biology of epidermal components
- Computational modeling for skin permeability prediction
- Molecular organization of stratum corneum
He has published extensively on skin barrier mechanisms, including landmark studies on ceramide-cholesterol interactions, cubic-to-lamellar phase transitions, and the role of keratin in barrier function. His work bridges dermatology, structural biology, and computational biophysics.
0Publications listed
