Lars Melholt Rasmussen

Lars Melholt Rasmussen is a Clinical Professor at the Department of Clinical Research, University of Southern Denmark, and affiliated with Odense University Hospital (OUH) and the Research Unit of Clinical Biochemistry (Odense). He is Head of the Center for Individualized Medicine in Arterial Diseases (CIMA) and Head of Research at the Department of Clinical Biochemistry and Pharmacology, OUH.

• University: University of Southern Denmark
• Hospital Affiliation: Odense University Hospital (OUH)
• Research Center: CIMA – Center for Individualized Medicine in Arterial Diseases
• ORCID: 0000-0001-5795-4794

Research Interests:
Lars Melholt Rasmussen specializes in clinical biochemistry with a focus on cardiovascular and renal research. His work spans proteomics, biomarker discovery, atherosclerosis, abdominal aortic aneurysm, diabetes, and somatic mutations in vascular diseases. He is deeply involved in personalized medicine approaches to cardiovascular disease prevention and risk estimation.

Recent Research Trends:
His recent publications highlight cutting-edge research in somatic mutations in atherosclerotic plaques, metabolic regulation in aneurysm formation (e.g., PDK/PDH axis), and innovative methods like microsampling for proteomic biomarker discovery. His work frequently appears in high-impact journals such as Circulation, Cardiovascular Research, and JCI Insight, reflecting strong translational and clinical relevance.

Scientific Projects:

• PREPARE: Personalised Risk Estimation and Prevention of Cardiovascular Disease (2022–2026)
• Functional Genomic Studies: Multi-omics analysis of age-related traits and diseases in twins

Advising and Grants:
He has supervised at least two academic works and is actively involved in major research projects funded by research councils. His collaborative network is extensive, involving national and international partners in cardiovascular genomics and clinical research.

Laboratories and Research Groups:
He leads research activities within the Research Unit of Clinical Biochemistry at OUH and the CIMA center, focusing on integrating omics technologies with clinical data for individualized vascular medicine.