Larry Anderson Jr.

Larry Anderson Jr., M.D., Ph.D., is a Professor in the Department of Internal Medicine at UT Southwestern Medical Center, specializing in the Division of Hematology and Oncology. His clinical expertise centers on bone marrow transplantation for plasma cell disorders including multiple myeloma, Waldenström's macroglobulinemia, amyloidosis, and other gammopathies.

Education:

• B.S. in Biomedical Sciences with honors (magna cum laude) from Texas A&M University
• M.D. and Ph.D. in Immunology from The University of Texas-Houston Health Science Center
• Internal Medicine Residency at Mayo Clinic, Rochester
• Medical Oncology Fellowship at University of Washington Medical Center and Fred Hutchinson Cancer Research Center

Research Focus: Dr. Anderson's work pioneers cancer immunology and immunotherapy approaches for multiple myeloma and stem cell transplantation. His investigations explore T-cell therapies, vaccine strategies against myeloma antigens, and mechanisms of graft-versus-tumor activity. He has developed novel protocols for DNA immunization targeting amyloid beta in Alzheimer's disease, demonstrating reduced autoimmune risks while maintaining efficacy.

Publication Trends: Recent publications (2017-2021) reveal intense focus on clinical trials for multiple myeloma therapeutics, including CAR T-cell therapy (idecabtagene vicleucel), antibody-drug conjugates (GSK2857916), and novel combinations (selinexor/bortezomib). His work spans from mechanistic immunology studies to large phase 3 trials (GRIFFIN, BOSTON), with growing emphasis on relapsed/refractory disease and treatment complications like secondary leukemias.

Scientific Recognition:

• Super Doctor designation by Texas Monthly
• Diplomate of American Board of Internal Medicine (Medical Oncology)

Professional Engagement: Active member of American Society of Hematology and Texas Medical Association. His clinical practice integrates advanced transplantation techniques with immunotherapeutic innovations, maintaining strong translational research connections between laboratory discoveries and patient care in hematologic malignancies.