Klarissa Jackson

Klarissa Jackson is an Assistant Professor at the UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill. Her research focuses on translational studies in drug metabolism and toxicology, particularly on adverse drug reactions and interindividual variability in drug response.

Key research areas include:

• Drug metabolism and toxicology
• Genetic and environmental factors affecting drug disposition
• Cytochrome P450 and UDP-glucuronosyltransferase enzymes
• Tyrosine kinase inhibitors (cancer therapy) and cannabidiol (epilepsy treatment)
• Structure-metabolism-toxicity relationships in drug discovery

Her recent publications highlight:

• CYP3A and CYP2C8 enzyme roles in tyrosine kinase inhibitor metabolism
• Hepatotoxicity of cannabinoids and chemotherapy drugs
• Sociocultural factors affecting BIPOC women in pharmacy academia
• 3D hepatocyte models for toxicity assessment
• Pharmacogenomics of drug metabolism