Kin Chan

Kin Chan is an Associate Professor in the Department of Biochemistry, Microbiology and Immunology at the University of Ottawa, conducting research at the intersection of cancer mutagenesis, DNA damage, and genome instability.

• Education: BSc from Caltech (1998), PhD from University of Washington/Fred Hutchinson Cancer Research Center (2008), Postdoctoral Fellowship at National Institute of Environmental Health Sciences (2016)
• Research Focus: Molecular origins of cancer mutations, DNA repair mechanisms, and APOBEC3 enzyme-driven hypermutation

His work combines wet lab and computational approaches to study mutagenesis signatures in cancers, particularly those induced by environmental agents and enzymatic processes. Recent projects explore repurposing cancer hypermutator enzymes like APOBEC3A for genetic engineering in budding yeast to develop biofuel applications.

Key publication trends include mutational signature analysis, DNA damage tolerance, and cross-species genomic instability studies. Dr. Chan's lab webpage provides details for prospective trainees and ongoing research collaborations.

Contact: Office in Roger Guindon Hall, Room 4234; Lab in Room 4233; Phone: 613-562-5800 ext. 8574