
About
Ken Prehoda is a Professor in the Department of Chemistry and Biochemistry at the University of Oregon, where he has been since 2001. His research focuses on biochemical processes governing cellular signaling, particularly protein-protein interactions during asymmetric cell division and stem cell development.
- B.A., California State University - Sacramento (1991)
- Ph.D., University of Wisconsin - Madison (1997)
- Postdoctoral Research, University of California, San Francisco (1997-2001)
Prehoda's lab investigates how environmental cues trigger molecular programs in cells, utilizing structural biology techniques like X-ray crystallography and NMR to analyze protein complexes. Key areas include PDZ domain regulation, MAGUK scaffolding proteins, and mechanisms of cellular polarization.
His recent publications highlight studies on asymmetric division in Drosophila neuroblasts, spindle orientation pathways, and the structural dynamics of signaling domains. Keywords across his work include Cell Biology, Developmental Biology, Structural Biology, and Signal Transduction.
- NIH Postdoctoral Fellow (2000-2001)
- Damon Runyon Scholar (2003-2006)
The Prehoda Lab combines structural, biochemical, and cell biological approaches to unravel regulated scaffolding in signaling pathways, with implications for understanding cellular organization and disease mechanisms.
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