Kenneth Hoehn

Kenneth Hoehn is an Assistant Professor in the Department of Biomedical Data Science at the Geisel School of Medicine, Dartmouth College. As a computational immunologist with expertise in evolutionary biology, he develops computational evolutionary approaches to trace cellular lineages, particularly B cells, in contexts such as infection, vaccination, cancer, and autoimmune diseases.

His research focuses on understanding adaptive immunity in conditions like

• COVID-19
• Food allergies
• Myasthenia gravis

through collaborations with experimental teams. Key projects include:

• Phylogenetic modeling of B cell responses
• Evolutionary signatures in immune repertoires
• Tracking B cell dissemination in autoimmune diseases
• Epigenetic regulation of memory B cells

Recent publications highlight trends in single-cell immunology, phylogenetic inference, and computational tools for analyzing B cell dynamics. His lab at Dartmouth integrates evolutionary genetics with high-resolution immune profiling.