Katherine Stott

Katherine Stott is a Researcher and Biophysics Facility Manager in the Department of Biochemistry at the University of Cambridge. Her research focuses on the organizational and regulatory roles of intrinsically disordered proteins in chromatin architecture and signaling complexes. She leads a group investigating how disordered regions encode function, particularly in linker histones and scaffold proteins, using techniques like X-ray scattering and NMR spectroscopy.

Key research areas include chromatin condensation mechanisms, phase-separated nuclear organization, and the assembly of signaling complexes. Her work has revealed how histone variants and post-translational modifications regulate chromatin structure and function. Recent findings on calcineurin scaffolding highlight the role of disordered regions in coordinating signaling pathways.

Dr. Stott’s group is equipped with advanced biophysical facilities, including solution-state scattering and NMR platforms. She collaborates internationally, leveraging national research centers for structural biology studies. Contact: ks123@cam.ac.uk.