Karl-Johan Malmberg

Karl-Johan Malmberg is a Professor at the University of Oslo, affiliated with the Faculty of Medicine and leading research at the Radiumhospitalet. His work focuses on Natural Killer (NK) cell biology and precision immunotherapy, with a strong emphasis on cancer immunology, HLA-KIR interactions, and cell therapy engineering. He collaborates extensively with the PRIMA - Precision Immunotherapy Alliance and contributes to translational research in hematopoietic stem cell transplantation and solid tumor immunotherapy.

• Expert in NK cell education and functional reprogramming
• Develops allogeneic cell therapies for leukemia and multiple myeloma
• Pioneers single-cell and high-dimensional analysis of immune compartments

Recent publications highlight innovations in NK cell migration inhibition via GPR56, NKG2A/C switch receptors, and nanoparticle-enhanced NK cell activation. His team drives computational tools like MetaGate for cytometry data integration.

Key affiliations include the Research Council of Norway Center of Excellence (PRIMA), with a focus on cell therapy translation and tumor immune microenvironment mapping.