Juri Rappsilber

Prof. Juri Rappsilber is a Professor at the Technical University of Berlin's Institute of Biotechnology and Group Leader of Research Unit E in the UniSysCat Cluster of Excellence. His affiliations include Visiting Professorship at Kyoto University (2017, JSPS Fellow) and Senior Research Fellowships at the Wellcome Trust (2009-2019). He leads the Rappsilber Laboratory, focused on developing mass spectrometry technologies to study protein structure and interactions.

Research interests center on proteomics, crosslinking mass spectrometry, and protein-network analysis. Key areas include:

• Functional protein networks through co-regulation studies
• Chromatin dynamics and mitotic chromosome composition
• In-cell structural proteomics integrating deep learning
• Development of bioorthogonal catalysis for medical applications

His publication record demonstrates consistent output in high-impact journals, with recent work emphasizing:

• Structural mechanisms of protein complexes (γ-tubulin, condensin)
• Crosslinking MS methodology innovation and error control
• Integration of AI with experimental structural biology
• Catalytic processes in bioinorganic systems

Awards and honors:

• EMBO Membership (2021)
• BSPR Lectureship (2014)
• Einstein Professorship (2011)
• Wellcome Trust Senior Research Fellow (2009-2019)
• Marie Curie Excellence Fellow (2005-2010)

He actively advises doctoral students, including DAAD Hilde-Domin Program recipients, and secures substantial funding through ERC Synergy Grants, Wellcome Trust awards, and national initiatives. The lab focuses on developing anti-cancer therapeutics and sustainable chemistry solutions while pursuing Green Lab Certification.