About
Jun Che is a Research Associate Professor at the School of Medicine, Southern University of Science and Technology (SUSTech), where he has worked since December 2020. He previously worked as a Postdoctoral Fellow and Associate Research Fellow at the University of Texas Health Science Center (UTHSA) from 2015 to 2020 and completed his Ph.D. in Genetics there in 2015. His academic journey includes a Master’s in Cytogenetics from Kunming Institute of Zoology (2004–2007) and a Bachelor of Engineering in Bioengineering from Xi’an Jiaotong University (2000–2004).
Research Focus: Dr. Che’s work revolves around DNA damage tolerance (DDT) in Saccharomyces cerevisiae, investigating how cells bypass DNA lesions during replication to maintain genome stability. His studies on translesion synthesis (TLS), template switching (TS), and PCNA ubiquitination have significant implications for understanding cancer, aging, and drug resistance. His publications span Nature Structural & Molecular Biology, PLoS Genetics, and EMBO Journal, with recent articles (2019–2021) focusing on DDT mechanisms and their biomedical relevance.
- Honors: CPRIT predoctoral fellowship (2011, 2012), 2021 Biomolecules publication on PCNA regulation.
- Email: chej@mail.sustech.edu.cn.
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