Jun Cao

Jun Cao is an organic chemistry researcher specializing in carbohydrate chemistry, enzyme inhibition, and spirocyclic compound synthesis. Current research focuses on developing fluorinated heptose phosphate analogues as inhibitors for bacterial lipopolysaccharide biosynthesis enzymes (HldA/HldE) and exploring spirocyclopropyl carbohydrates for biochemical applications.

• Active in interdisciplinary research combining organic synthesis with microbiology and chemical biology
• Published 4 peer-reviewed articles between 2021-2024
• Collaborates with international researchers in carbohydrate and enzyme research fields

Recent work emphasizes the design of bioactive molecules for antimicrobial applications, with publications in Bioorganic Chemistry, Tetrahedron, and Organic Letters. The research portfolio includes synthesis methodology, phosphorylation strategies, and enzyme-targeting drug development.

Thesis work on "Synthesis of heptose mimetics as inhibitors of bacterial enzymes or modulators of inflammation" (2022) demonstrates expertise in carbohydrate-based therapeutic agent design. Collaborations extend to researchers like S.P. Vincent, X. De Bolle, and E. Déziel.