Joëlle Rüegg

Joëlle Rüegg is a Professor at Uppsala University, affiliated with the Department of Organismal Biology and the Institute for Research on Conflicts of Interest in Sustainable Social Transformation. Her research focuses on endocrine disruptors' impact on neurodevelopment through epigenetic mechanisms, integrating molecular toxicology with regulatory policy. Key projects include the Horizon 2020-funded ENDpoiNTs and Formas-supported initiatives on chemical mixtures and blood-brain barrier effects.

• Department of Organismal Biology, Uppsala University
• Institute for Research on Conflicts of Interest in Sustainable Social Transformation

Research Interests: Dr. Rüegg investigates how environmental chemicals, particularly endocrine disrupting chemicals (EDCs), alter brain development via epigenetic changes. Her work bridges molecular mechanisms (e.g., DNA methylation, transporter interactions) with human health outcomes like neurodevelopmental disorders, gender-dysphoria associations, and behavioral changes. She emphasizes regulatory applications, developing in vitro models (e.g., C17.2 cell line) and strategies for chemical mixture risk assessment.

Publication Trends: Recent articles (2023-2025) explore EDCs' effects on DNA methylation patterns, neurodevelopmental disorders, and cross-species models (zebrafish, mice). Her work spans environmental epidemiology (SELMA, SKDS studies), molecular toxicology, and policy-oriented risk assessment frameworks like PARC and SMACH.