Joseph R Pisegna

Joseph R Pisegna is a Professor-in-Residence at the University of California, Los Angeles, with joint appointments in the Department of Medicine and Department of Human Genetics. His work bridges clinical gastroenterology and genetic research.

• Research Interests: Gastrointestinal diseases, pancreatic pathophysiology, hepatic metabolism, microbiome interactions, and neuropeptide regulation of appetite.

Publications highlight expertise in:

• Pancreatic disorders and alcohol-related pathologies
• Microbiome alterations in obesity and liver disease
• Neuropeptide signaling in metabolic regulation
• Genetic and molecular mechanisms in hepatocellular carcinoma

Scientific Contributions:

• NIH-funded studies on gastrointestinal hormonal regulation (2010–2015)
• Principal investigator for single-cell RNA sequencing projects (2019)
• Developed machine learning models for pancreatic cancer detection (2023)

Publications reflect collaborations across medicine, genetics, and computational biology. His work emphasizes translational approaches to gastrointestinal and metabolic diseases.