
About
Dr Joseph Kwong is a Lecturer in Bioscience at the Keele University School of Medicine, located in the David Weatherall Building. His research focuses on cancer biology, immunology, and drug discovery, with a particular emphasis on ovarian, endometrial, and hepatocellular cancers. He employs advanced techniques such as CRISPR/Cas9, AI-driven drug screening, and multiplex immunohistochemistry to investigate cancer mechanisms and therapeutic targets.
His work explores tumor-immune interactions, including the roles of lymphotoxin and Wnt/β-catenin signaling in cancer progression and immune evasion. Dr Kwong also investigates molecular biomarkers, such as miR-200 and sfTSLP, and evaluates novel therapies like green tea extract prodrugs. His studies often integrate clinical outcomes, such as DNA mismatch repair status in endometrial cancers and pregnancy outcomes in IVF patients.
Key research themes include:
- Cancer chemoresistance and recurrence mechanisms
- Immune cell dynamics in tumors and reproductive tissues
- Epigenetic and genetic drivers of gynecologic and liver cancers
- Development of patient-derived organoid models for drug testing
While no awards or grants are explicitly listed, his extensive publication record reflects active engagement in translational cancer research. Collaborations with clinical teams at the University Hospitals of North Midlands NHS Trust suggest a focus on bridging laboratory findings to clinical applications.
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