Jon Christopher Aster

Jon Christopher Aster is a Professor of Pathology at Brigham and Women's Hospital, affiliated with Harvard Medical School. His research focuses on Notch signaling in cancer, particularly its role in T cell development and transformation, using genomic approaches like ChIP-Seq and collaborations across structural biology, bioinformatics, and animal modeling.

• Brigham and Women's Hospital
• Harvard Medical School

Research interests include:

• Notch signaling in leukemia and T cell malignancies
• Transcriptional regulation via genome-wide approaches
• Post-translational modifications in signaling pathways
• Immune interactions in tumor microenvironments

Recent articles span Notch-related cancer mechanisms, immunotherapy applications, and collaborative multi-omics studies. Scientific awards and honors are not explicitly detailed in the provided text.