John Lawrence Wallace

John Lawrence Wallace is an Adjunct Professor at the Cumming School of Medicine, University of Calgary, and a Full Member of the Inflammation Research Network. His work focuses on gastrointestinal inflammation, cardiovascular inflammation, and hydrogen sulfide-based therapeutics.

Educational Background:

• M.B.A. (with distinction), University of Birmingham (2008)
• Ph.D., Medical Science, University of Toronto (1983)
• M.Sc., Biology, Queen's University (1980)
• B.Sc., Biology, Queen's University (1979)

Dr. Wallace's research explores inflammation's role in tissue injury and repair, with emphasis on gastrointestinal and cardiovascular inflammation. He identified NSAID-induced stomach damage mechanisms and pioneered hydrogen sulfide's use in anti-inflammatory drugs through companies like NicOx and Antibe Therapeutics.

His 15 most recent publications (2016–2020) highlight trends in gasotransmitter-based drug development for gastrointestinal diseases, cancer chemoprevention, and inflammation resolution. Key areas include hydrogen sulfide's protective effects in colitis, NSAID alternatives, microbiome interactions, and mucosal repair.

Scientific Awards:

• Fellow, Canadian Association of Gastroenterology (2014)
• Heymans Memorial Award, University of Gent, Belgium (2013)
• William Harvey Medal, UK (2011)
• Fellow, Royal Society of Canada (2008)
• Scientific Achievement and Innovation Award, BioAlberta (2007)
• Fellow, Brazilian Academy of Science (2006)
• Gaddum Medal, British Pharmacological Society (2006)
• Career Investigator Award, Pharmacological Society of Canada (2006)