John Hilton

John Hilton is an Associate Professor of Medicine at the University of Ottawa's Faculty of Medicine, serving as a staff medical oncologist at the Ottawa Hospital Cancer Centre and Clinician Investigator at the Ottawa Hospital Research Institute's Cancer Therapeutics Program. He leads Breast Cancer Disease Site Research and oversees the Clinical Trials Office. His clinical expertise and research focus on improving care for breast and head and neck cancer patients, with specialization in early drug development for metastatic disease.

Education:

• MDCM from McGill University (2005)
• BSc in Human Genetics (2001)
• BSc from McGill University (1999)

Research interests center on translational oncology with emphasis on immunotherapy resistance mechanisms, novel therapeutic combinations, and supportive care strategies in chemotherapy. His work bridges clinical practice and drug development, particularly in targeted therapies for solid tumors and symptom management.

Key publication themes include PD-1 resistance mechanisms in cancer immunotherapy, neutropenia prophylaxis protocols, and optimizing antiemetic regimens for high-risk patients. He has contributed to understanding links between obstructive sleep apnea and cancer incidence through large cohort studies.

Current initiatives focus on clinical trial innovation, precision medicine approaches, and patient-centered care improvements in oncology. He collaborates widely across institutions to advance multidisciplinary cancer research programs.