About
Professor Jing Chen at the University of Chicago focuses on Cancer Metabolism and Signal Transduction, investigating how metabolic networks intersect with oncogenic pathways. She holds appointments in the Department of Medicine-Hematology and Oncology, with research spanning dietary impacts on tumor growth, metabolic enzyme regulation, and immunotherapy enhancement.
Education:
- BS in Molecular Biology, University of Science and Technology of China (1994)
- PhD in Biochemistry & Cell Biology, Emory University (2001)
- Postdoc in Cancer Biology, HHMI & Harvard Medical School (2004)
Research Interests: Dr. Chen's work explores Cancer Metabolism, Diet and Nutrition, and Signal Transduction, particularly the role of metabolites as signaling molecules. Her studies link dietary factors to oncogenic mutations and examine metabolic reprogramming in tumors.
Publication Trends: Her recent articles emphasize trans-vaccenic acid in immunotherapy, Lyso-PAF signaling, and AMPK/PP2A dynamics. Keywords span Molecular Biology, Cell Metabolism, and Immunology, reflecting interdisciplinary approaches.
Scientific Awards:
- LLS Fellow (2004-2007)
- GCC Distinguished Cancer Scholar (2006)
- ACS Basic Research Scholar (2008-2012)
- Winship 5K Scholar (2014-2019)
- R. Randall Rollins Chair in Oncology (2018-2020)
Grants: She leads NIH-funded projects including R01CA276568-01 (2022-2027) on dietary trans-vaccenic acid and anti-tumor immunity, and R01CA174786 (2014-2025) on AMPK homeostasis via PP2A. Her lab specializes in metabolic signaling and translational oncology.
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