About
Dr. Jianfeng Lin is a Senior Research Scientist and Managing Director of the Yale CryoEM Resource at Yale University's Department of Molecular Biophysics and Biochemistry. He holds a PhD in Biochemistry and Molecular Biology from Xiamen University (2008) and completed postdoctoral training at Brandeis University and UT Southwestern Medical Center. His research focuses on understanding ciliary motility mechanisms, dynein dynamics, and ciliopathies using cryoelectron tomography and structural biology approaches. He leads the unification of Yale's electron microscopy facilities into the Yale CryoEM Resource, supporting both internal and external research communities.
Education:
- BS in Biological Sciences, Xiamen University (2003)
- PhD in Biochemistry and Molecular Biology, Xiamen University (2008)
- Postdoctoral Associate, Brandeis University (2015)
Research interests span molecular mechanisms of ciliary dysfunction, structural characterization of axonemal components, and cryoEM applications in biomedical research. His work has revealed structural defects in ciliopathies, dynein regulation pathways, and conserved axonemal architectures across species. Recent studies highlight advancements in cryoEM techniques and their role in resolving complex cellular structures.
Advising and Facilities: As Managing Director of the Yale CryoEM Resource, Dr. Lin oversees a state-of-the-art facility supporting structural biology research. His grants and collaborations focus on advancing cryoEM technology and its application to biomedical problems.
Labs/Teams: Director of the Yale CryoEM Resource, a centralized facility integrating cryo-electron microscopy capabilities for Yale researchers.
